Fundamentals of Pulmonary Tuberculosis and Its Complications

The therapy of pulmonary tuberculosis and its complications by thiosemicarbazone.

Domagk is considered the pioneer of chemotherapy in tuberculosis with thiosemicarbazones. He studied, in cooperation with his collaborators, a large number of thiosemicarbazones developed by the chemists Behnisch, Mietzsch and Schmidt, has found that the 4-acetylaminobenzaldeydethiosemicarbazone was the most efficacious substance against the tubercle bacillus. This compound, according to Domagk...

Complications of Pulmonary Tuberculosis

Pulmonary resection can improve treatment outcome in re-treatment pulmonary tuberculosis and its complications

n Society http cense. Abstract Background: Pulmonary tuberculosis (TB) is a widely spread disease, usually treated by multidrug therapy, nevertheless there are increasing number of cases in which medical treatment fails and requires surgical intervention specially those with large cavitary lesions or persistent sputum positive for Ziehl Neelsen (ZN) stain. Our objective was to assess the role o...

BCG vaccine and pulmonary tuberculosis

Tuberculosis (TB) is one of the most important public health problems in the world and has been declared as a global emergency by the World Health Organization (WHO) in 1993. Bacillus Calmette-Guérin (BCG) is one of the first developed vaccines to prevent TB. Unfortunately, BCG vaccine has had a limited duration of protection and has shown controversial and variable levels of efficacy, especial...

Pulmonary Tuberculosis